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nir fluorescence signal  (LI-COR)


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    LI-COR nir fluorescence signal
    FIGURE 5. Athymic mice bearing SKBr3-luc xenografts were sacrificed at 5, 24, 48, and 72 h after intravenous injection of (111In-DTPA)n-trastuzumab-(IRDye800)m, and major organs were dissected. (A) Notched box-and-whisker statistical plots compare TMRs obtained with g-scintillation counting for nuclear counts and <t>NIR</t> fluorescence imaging for optical counts at various time points. There was no statistical significance in TMRs observed at various time points within each imaging modality, but TMRs obtained with optical imaging were statis- tically higher than those obtained with nuclear imaging (P , 0.0001) at each time point. (B) Plots of nuclear versus optical TMRs obtained with nuclear imaging and optical imaging for these mice yielded an R value of 0.9476 (P , 0.0001), suggesting that results obtained from nuclear imaging and optical imaging are highly correlated. (C) When TMRs were compared on a consistent basis with respect to tissue weight (g), the statistical differences between optical and nuclear imaging are abolished.
    Nir Fluorescence Signal, supplied by LI-COR, used in various techniques. Bioz Stars score: 99/100, based on 36526 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/nir fluorescence signal/product/LI-COR
    Average 99 stars, based on 36526 article reviews
    nir fluorescence signal - by Bioz Stars, 2026-05
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    Images

    1) Product Images from "Dual-labeled trastuzumab-based imaging agent for the detection of human epidermal growth factor receptor 2 overexpression in breast cancer."

    Article Title: Dual-labeled trastuzumab-based imaging agent for the detection of human epidermal growth factor receptor 2 overexpression in breast cancer.

    Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine

    doi: 10.2967/jnumed.107.042234

    FIGURE 5. Athymic mice bearing SKBr3-luc xenografts were sacrificed at 5, 24, 48, and 72 h after intravenous injection of (111In-DTPA)n-trastuzumab-(IRDye800)m, and major organs were dissected. (A) Notched box-and-whisker statistical plots compare TMRs obtained with g-scintillation counting for nuclear counts and NIR fluorescence imaging for optical counts at various time points. There was no statistical significance in TMRs observed at various time points within each imaging modality, but TMRs obtained with optical imaging were statis- tically higher than those obtained with nuclear imaging (P , 0.0001) at each time point. (B) Plots of nuclear versus optical TMRs obtained with nuclear imaging and optical imaging for these mice yielded an R value of 0.9476 (P , 0.0001), suggesting that results obtained from nuclear imaging and optical imaging are highly correlated. (C) When TMRs were compared on a consistent basis with respect to tissue weight (g), the statistical differences between optical and nuclear imaging are abolished.
    Figure Legend Snippet: FIGURE 5. Athymic mice bearing SKBr3-luc xenografts were sacrificed at 5, 24, 48, and 72 h after intravenous injection of (111In-DTPA)n-trastuzumab-(IRDye800)m, and major organs were dissected. (A) Notched box-and-whisker statistical plots compare TMRs obtained with g-scintillation counting for nuclear counts and NIR fluorescence imaging for optical counts at various time points. There was no statistical significance in TMRs observed at various time points within each imaging modality, but TMRs obtained with optical imaging were statis- tically higher than those obtained with nuclear imaging (P , 0.0001) at each time point. (B) Plots of nuclear versus optical TMRs obtained with nuclear imaging and optical imaging for these mice yielded an R value of 0.9476 (P , 0.0001), suggesting that results obtained from nuclear imaging and optical imaging are highly correlated. (C) When TMRs were compared on a consistent basis with respect to tissue weight (g), the statistical differences between optical and nuclear imaging are abolished.

    Techniques Used: Injection, Whisker Assay, Imaging, Optical Imaging



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    FIGURE 5. Athymic mice bearing SKBr3-luc xenografts were sacrificed at 5, 24, 48, and 72 h after intravenous injection of (111In-DTPA)n-trastuzumab-(IRDye800)m, and major organs were dissected. (A) Notched box-and-whisker statistical plots compare TMRs obtained with g-scintillation counting for nuclear counts and <t>NIR</t> fluorescence imaging for optical counts at various time points. There was no statistical significance in TMRs observed at various time points within each imaging modality, but TMRs obtained with optical imaging were statis- tically higher than those obtained with nuclear imaging (P , 0.0001) at each time point. (B) Plots of nuclear versus optical TMRs obtained with nuclear imaging and optical imaging for these mice yielded an R value of 0.9476 (P , 0.0001), suggesting that results obtained from nuclear imaging and optical imaging are highly correlated. (C) When TMRs were compared on a consistent basis with respect to tissue weight (g), the statistical differences between optical and nuclear imaging are abolished.
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    FIGURE 5. Athymic mice bearing SKBr3-luc xenografts were sacrificed at 5, 24, 48, and 72 h after intravenous injection of (111In-DTPA)n-trastuzumab-(IRDye800)m, and major organs were dissected. (A) Notched box-and-whisker statistical plots compare TMRs obtained with g-scintillation counting for nuclear counts and <t>NIR</t> fluorescence imaging for optical counts at various time points. There was no statistical significance in TMRs observed at various time points within each imaging modality, but TMRs obtained with optical imaging were statis- tically higher than those obtained with nuclear imaging (P , 0.0001) at each time point. (B) Plots of nuclear versus optical TMRs obtained with nuclear imaging and optical imaging for these mice yielded an R value of 0.9476 (P , 0.0001), suggesting that results obtained from nuclear imaging and optical imaging are highly correlated. (C) When TMRs were compared on a consistent basis with respect to tissue weight (g), the statistical differences between optical and nuclear imaging are abolished.
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    Image Search Results


    FIGURE 5. Athymic mice bearing SKBr3-luc xenografts were sacrificed at 5, 24, 48, and 72 h after intravenous injection of (111In-DTPA)n-trastuzumab-(IRDye800)m, and major organs were dissected. (A) Notched box-and-whisker statistical plots compare TMRs obtained with g-scintillation counting for nuclear counts and NIR fluorescence imaging for optical counts at various time points. There was no statistical significance in TMRs observed at various time points within each imaging modality, but TMRs obtained with optical imaging were statis- tically higher than those obtained with nuclear imaging (P , 0.0001) at each time point. (B) Plots of nuclear versus optical TMRs obtained with nuclear imaging and optical imaging for these mice yielded an R value of 0.9476 (P , 0.0001), suggesting that results obtained from nuclear imaging and optical imaging are highly correlated. (C) When TMRs were compared on a consistent basis with respect to tissue weight (g), the statistical differences between optical and nuclear imaging are abolished.

    Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine

    Article Title: Dual-labeled trastuzumab-based imaging agent for the detection of human epidermal growth factor receptor 2 overexpression in breast cancer.

    doi: 10.2967/jnumed.107.042234

    Figure Lengend Snippet: FIGURE 5. Athymic mice bearing SKBr3-luc xenografts were sacrificed at 5, 24, 48, and 72 h after intravenous injection of (111In-DTPA)n-trastuzumab-(IRDye800)m, and major organs were dissected. (A) Notched box-and-whisker statistical plots compare TMRs obtained with g-scintillation counting for nuclear counts and NIR fluorescence imaging for optical counts at various time points. There was no statistical significance in TMRs observed at various time points within each imaging modality, but TMRs obtained with optical imaging were statis- tically higher than those obtained with nuclear imaging (P , 0.0001) at each time point. (B) Plots of nuclear versus optical TMRs obtained with nuclear imaging and optical imaging for these mice yielded an R value of 0.9476 (P , 0.0001), suggesting that results obtained from nuclear imaging and optical imaging are highly correlated. (C) When TMRs were compared on a consistent basis with respect to tissue weight (g), the statistical differences between optical and nuclear imaging are abolished.

    Article Snippet: Cells were suspended in 100 mL of PBS and added to a microtiter plate, and the NIR fluorescence signal was obtained by use of an Odyssey infrared imaging system (Li-Cor Biosciences).

    Techniques: Injection, Whisker Assay, Imaging, Optical Imaging